Anti-AKR1B1 antibody produced in mouse
SIGMA/SAB1409018 - purified immunoglobulin, buffered aqueous solution
Synonym: ADR; ALDR1; ALR2; AR; MGC1804
Product Type: Chemical
Western Blotting Western Blot analysis of AKR1B1 expression in transfected 293T cell line by AKR1B1 polyclonal antibody. Lanes Lane 1: AKR1B1 transfected lysate (34.76 kDa). Lane 2: Non-transfected lysate.
Western Blotting AKR1B1 polyclonal antibody. Western Blot analysis of AKR1B1 expression in human kidney.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 34.76 kDa |
| NCBI accession no. | BC000260   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P15121 |
| Biochem/physiol Actions: | Aldo-keto reductase family 1, member B1 (AKR1B1) takes part in the reduction of aldehydes. It can be induced by proteasome inhibitors in human colon cancer cell lines HT-29 and SW-480. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. (provided by RefSeq) |
| Immunogen: | AKR1B1 (AAH00260, 1 a.a. ~ 316 a.a) full-length human protein. Sequence MASRLLLNNGAKMPILGLGTWKSPP |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |