Anti-HLA-DRA antibody produced in mouse
SIGMA/SAB1409196 - purified immunoglobulin, buffered aqueous solution
Synonym: HLA-DRA1
Product Type: Chemical
Western Blotting HLA-DRA polyclonal antibody. Western Blot analysis of HLA-DRA expression in human spleen.
Western Blotting Western Blot analysis of HLA-DRA expression in transfected 293T cell line by HLA-DRA polyclonal antibody. Lanes Lane 1: HLA-DRA transfected lysate (27.94 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 28.6 kDa |
| NCBI accession no. | NM_019111   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P01903 |
| General description: | HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. (provided by RefSeq) |
| Immunogen: | HLA-DRA (NP_061984.2, 1 a.a. ~ 254 a.a) full-length human protein. Sequence MAISGVPVLGFFIIAVLMSAQESWA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |