Anti-KIAA0319L antibody produced in mouse
SIGMA/SAB1409827 - purified immunoglobulin, buffered aqueous solution
Synonym: KIAA1837; PKD1-like; PP791; RP4-765A10.3
Product Type: Chemical
Western Blotting KIAA0319L polyclonal antibody. Western Blot analysis of KIAA0319L expression in human kidney.
Western Blotting Western Blot analysis of KIAA0319L expression in transfected 293T cell line by KIAA0319L polyclonal antibody. Lanes Lane 1: KIAA0319L transfected lysate (115.39 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 115.6 kDa |
| NCBI accession no. | BC014530.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q8IZA0 |
| Biochem/physiol Actions: | KIAA0319-like (KIAA0319L) protein is involved in neuronal migration in the developing brain. It plays a role in learning and cognition. KIAA0319L works as a receptor for adeno-associated virus infection. KIAA0319L gene is considered a dyslexia susceptibility gene that is associated with developmental dyslexia, a common childhood learning disorder. Overexpression of the KIAA0319L gene is observed in peripheral blood cells from patients with systemic lupus erythematosus (SLE). KIAA0319L protein is linked with polycystic kidney disease. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | KIAA0319-like (KIAA0319L) protein is localized in the nucleus and cytoplasm. This protein is a type-I transmembrane protein with five immunoglobulin-like domains, known as polycystic kidney disease (PKD) domains present in the ectodomain. The KIAA0319L gene is mapped on the human chromosome at 1p34.3. |
| Immunogen: | KIAA0319L (AAH14530.1, 1 a.a. ~ 1049 a.a) full-length human protein. Sequence MEKRLGVKPNPASWILSGYYWQTSA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |