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Monoclonal Anti-CAMK2B antibody produced in mouse

SIGMA/SAB1409845 - clone 6D6, purified immunoglobulin, buffered aqueous solution

Synonym: CAM2; CAMK2; CAMKB; MGC29528

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SAB1409845-100UG 100 µg
$580.00
1/EA
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Immunofluorescence Immunofluorescence of monoclonal antibody to CAMK2B on HeLa cell. [antibody concentration 25 μg/mL]
Western Blotting CAMK2B monoclonal antibody, clone 6D6. Western Blot analysis of CAMK2B expression in HeLa.
Western Blotting QC Western Blot detection against Immunogen (36.52 kDa).

 

antibody form purified immunoglobulin
antibody product type primary antibodies
biological source mouse
clone 6D6, monoclonal
conjugate unconjugated
form buffered aqueous solution
isotype IgG1κ
mol wt antigen 36.52 kDa
NCBI accession no. NM_172081 
Quality Level 100 
shipped in dry ice
species reactivity human
storage temp. −20°C
target post-translational modification unmodified
technique(s) indirect ELISA: suitable
  indirect immunofluorescence: suitable
  western blot: 1-5 μg/mL
UniProt accession no. Q13554 
Biochem/physiol Actions: Calcium/calmodulin dependent protein kinase II β (CAMK2B) may bind to calmodulin. It has been associated with major depressive disorder.
General description: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. (provided by RefSeq)
Immunogen: CAMK2B (NP_742078, 405 a.a. ~ 502 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
FEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPL
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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