Anti-NR1I2 antibody produced in mouse
SIGMA/SAB1409956 - purified immunoglobulin, buffered aqueous solution
Synonym: BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to NR1I2 on HepG2 cell. [antibody concentration 10 μg/mL]
Western Blotting NR1I2 polyclonal antibody. Western Blot analysis of NR1I2 expression in rat liver.
Western Blotting Western Blot analysis of NR1I2 expression in transfected 293T cell line by NR1I2 polyclonal antibody. Lanes Lane 1: NR1I2 transfected lysate (47.74 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 49.8 kDa |
| NCBI accession no. | NM_003889.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | O75469 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. (provided by RefSeq) |
| Immunogen: | NR1I2 (NP_003880.3, 1 a.a. ~ 434 a.a) full-length human protein. Sequence MEVRPKESWNHADFVHCEDTESVPG |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |