Anti-CYP3A7 antibody produced in rabbit
SIGMA/SAB1410275 - purified immunoglobulin, buffered aqueous solution
Synonym: CP37; P450-HFLA
Product Type: Chemical
Western Blotting Western Blot analysis of CYP3A7 expression in transfected 293T cell line by CYP3A7 polyclonal antibody. Lanes Lane 1: CYP3A7 transfected lysate (57.50 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 57.5 kDa |
| NCBI accession no. | NM_000765.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P24462 |
| General description: | This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. (provided by RefSeq) |
| Immunogen: | CYP3A7 (NP_000756.1, 1 a.a. ~ 503 a.a) full-length human protein. Sequence MDLIPNLAVETWLLLAVSLILLYLY |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |