Anti-CYP27A1 antibody produced in rabbit
SIGMA/SAB1410281 - purified immunoglobulin, buffered aqueous solution
Synonym: CP27; CTX; CYP27
Product Type: Chemical
Western Blotting Western Blot analysis of CYP27A1 expression in transfected 293T cell line by CYP27A1 polyclonal antibody. Lanes Lane 1: CYP27A1 transfected lysate (60.20 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 60.2 kDa |
| NCBI accession no. | NM_000784.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q02318 |
| General description: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. (provided by RefSeq) |
| Immunogen: | CYP27A1 (NP_000775.1, 1 a.a. ~ 531 a.a) full-length human protein. Sequence MAALGCARLRWALRGAGRGLCPHGA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |