Anti-FCER1A antibody produced in rabbit
SIGMA/SAB1410373 - purified immunoglobulin, buffered aqueous solution
Synonym: FCE1A; FcERI
Product Type: Chemical
Western Blotting Western Blot analysis of FCER1A expression in transfected 293T cell line by FCER1A polyclonal antibody. Lanes Lane 1: FCER1A transfected lysate (29.60 kDa). Lane 2: Non-transfected lysate.
Western Blotting FCER1A rabbit polyclonal antibody. Western Blot analysis of FCER1A expression in human kidney.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 29.6 kDa |
| NCBI accession no. | NM_002001.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P12319 |
| General description: | The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM |
| Immunogen: | FCER1A (NP_001992.1, 1 a.a. ~ 257 a.a) full-length human protein. Sequence MAPAMESPTLLCVALLFFAPDGVLA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |