Anti-GSTM5 antibody produced in rabbit
SIGMA/SAB1410588 - purified immunoglobulin, buffered aqueous solution
Synonym: GSTM5-5; GTM5
Product Type: Chemical
Western Blotting GSTM5 rabbit polyclonal antibody. Western Blot analysis of GSTM5 expression in mouse liver.
Western Blotting Western Blot analysis of GSTM5 expression in transfected 293T cell line by GSTM5 polyclonal antibody. Lanes Lane 1: GSTM5 transfected lysate (25.70 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 25.7 kDa |
| NCBI accession no. | NM_000851.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P46439 |
| General description: | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual′s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. (provided by RefSeq) |
| Immunogen: | GSTM5 (NP_000842.2, 1 a.a. ~ 218 a.a) full-length human protein. Sequence MPMTLGYWDIRGLAHAIRLLLEYTD |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |