Anti-MYOD1 antibody produced in rabbit
SIGMA/SAB1410813 - purified immunoglobulin, buffered aqueous solution
Synonym: MYF3; MYOD; PUM; bHLHc1
Product Type: Chemical
Western Blotting MYOD1 rabbit polyclonal antibody. Western Blot analysis of MYOD1 expression in mouse spleen.
Western Blotting Western Blot analysis of MYOD1 expression in transfected 293T cell line by MYOD1 polyclonal antibody. Lanes Lane 1: MYOD1 transfected lysate (34.50 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 34.5 kDa |
| NCBI accession no. | NM_002478.4   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P15172 |
| Biochem/physiol Actions: | Myogenic differentiation 1 (MYOD1) associates with histone-modifying enzymes and stimulates muscle differentiation by elevating the expression of histone H3 mono methyl K4 (H3K4me1) and histone H3 acetyl 27 (H3K27ac). MyoD1 staining can be considered as a key adjunct in the sorting of pediatric soft-tissue sarcomas. Mutation in the gene is associated with the pathogenesis of perinatally lethal fetal akinesia. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Myogenic differentiation 1 (MYOD1) is encoded by the gene mapped to human chromosome 11p15.1. The encoded protein belongs to the basic helix-loop-helix (bHLH) family of transcription factors. MYOD1 is expressed exclusively during normal skeletal muscle myogenesis and in rhabdomyosarcomas. |
| Immunogen: | MYOD1 (NP_002469.2, 1 a.a. ~ 320 a.a) full-length human protein. Sequence MELLSPPLRDVDLTAPDGSLCSFAT |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |