Anti-ATP1B3 antibody produced in rabbit
SIGMA/SAB1410841 - purified immunoglobulin, buffered aqueous solution
Synonym: ATPB-3; CD298; FLJ29027
Product Type: Chemical
Western Blotting Western Blot analysis of ATP1B3 expression in transfected 293T cell line by ATP1B3 polyclonal antibody. Lanes Lane 1: ATP1B3 transfected lysate (31.50 kDa). Lane 2: Non-transfected lysate.
Western Blotting ATP1B3 rabbit polyclonal antibody. Western Blot analysis of ATP1B3 expression in PC-12.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 31.5 kDa |
| NCBI accession no. | NM_001679   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P54709 |
| Biochem/physiol Actions: | ATPase Na+/K+ transporting subunit Β 3 (ATP1B3) suppress enterovirus 71 (EV71) replication by elevating the production of type-I interferons, which might act as a potential target in treatment of EV71 infection. The encoded protein is also involved in the regulation of the immune response. Experimental study suggest that ATP1B3 can control restriction of HIV-1 production and nuclear factor Κ B (NF-ΚB) activation in a bone marrow stromal cell antigen 2 (BST-2) dependent manner. Elevated expression of ATP1B3 has been observed in colon and lung cancer. |
| General description: | ATPase Na+/K+ transporting subunit Β 3 (ATP1B3) is a 43kDa protein, encoded by the gene mapped to human chromosome 3q23. The encoded protein is a member of subfamily of Na+/K+ -ATPases. |
| Immunogen: | ATP1B3 (NP_001670.1, 1 a.a. ~ 279 a.a) full-length human protein. Sequence MTKNEKKSLNQSLAEWKLFIYNPTT |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |