Anti-PFKM antibody produced in rabbit
SIGMA/SAB1410958 - purified immunoglobulin, buffered aqueous solution
Synonym: GSD7; MGC8699; PFK-1; PFK-M; PFKX
Product Type: Chemical
Western Blotting Western Blot analysis of PFKM expression in transfected 293T cell line by PFKM polyclonal antibody. Lanes Lane 1: PFKM transfected lysate (85.20 kDa). Lane 2: Non-transfected lysate.
Western Blotting PFKM rabbit polyclonal antibody. Western Blot analysis of PFKM expression in mouse lung.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 85.2 kDa |
| NCBI accession no. | NM_000289   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P08237 |
| Biochem/physiol Actions: | Phosphofructokinase muscle (PFKM) functions as a rate-limiting enzyme in glycolysis. Aberrations in the gene expression cause Tarui disease and might also lead to non-insulin-dependent diabetes mellitus (NIDDM). Mutation of the gene might also increases the risk of susceptibility to breast cancer. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Phosphofructokinase muscle (PFKM) is a subunit of the mammalian tetramer phosphofructokinase. It is encoded by the gene mapped to human chromosome 12q13.1. PFKM is expressed in muscle, red blood cells, thyroid and brain. |
| General description: | The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phospha |
| Immunogen: | PFKM (NP_000280.1, 1 a.a. ~ 780 a.a) full-length human protein. Sequence MTHEEHHAAKTLGIGKAIAVLTSGG |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |