Anti-PTGIS antibody produced in rabbit
SIGMA/SAB1411144 - purified immunoglobulin, buffered aqueous solution
Synonym: CYP8; CYP8A1; MGC126858; MGC126860; PGIS; PTGI
Product Type: Chemical
Western Blotting Western Blot analysis of PTGIS expression in transfected 293T cell line by PTGIS polyclonal antibody. Lanes Lane 1: PTGIS transfected lysate (57.10 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 57.1 kDa |
| NCBI accession no. | NM_000961.3   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q16647 |
| General description: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. (provided by RefSeq) |
| Immunogen: | PTGIS (NP_000952.1, 1 a.a. ~ 500 a.a) full-length human protein. Sequence MAWAALLGLLAALLLLLLLSRRRTR |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |