Anti-RAD51C antibody produced in rabbit
SIGMA/SAB1411179 - purified immunoglobulin, buffered aqueous solution
Synonym: MGC104277; RAD51L2
Product Type: Chemical
Western Blotting Western Blot analysis of RAD51C expression in transfected 293T cell line by RAD51C polyclonal antibody. Lanes Lane 1: RAD51C transfected lysate (42.20 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 42.2 kDa |
| NCBI accession no. | NM_058216   |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | O43502 |
| General description: | This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. (provided by RefSeq) |
| Immunogen: | RAD51C (NP_478123.1, 1 a.a. ~ 376 a.a) full-length human protein. Sequence MRGKTFRFEMQRDLVSFPLSPAVRV |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |