Anti-RLBP1 antibody produced in rabbit
SIGMA/SAB1411195 - purified immunoglobulin, buffered aqueous solution
Synonym: CRALBP; MGC3663
Product Type: Chemical
Western Blotting RLBP1 rabbit polyclonal antibody. Western Blot analysis of RLBP1 expression in HeLa.
Western Blotting Western Blot analysis of RLBP1 expression in transfected 293T cell line by RLBP1 polyclonal antibody. Lanes Lane 1: RLBP1 transfected lysate (36.50 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 36.5 kDa |
| NCBI accession no. | NM_000326.3   |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P12271 |
| Biochem/physiol Actions: | Retinaldehyde binding protein 1 (RLBP1) plays a vital role in mammalian vision by directing 11-cis-retinoids for the conversion of photobleached opsin molecules into photosensitive visual pigments. Genetic variations in the gene leads to various autosomal recessive progressive retinopathy, including Bothnia dystrophy (BD) and retinitis, punctata albescens (RPA), Newfoundland rod-cone dystrophy (NFRCD), retinitis pigmentosa (RP) and fundus albipunctatus (FA). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Retinaldehyde binding protein 1 (RLBP1) mapped to human chromosome 15q26, encodes cellular retinaldehyde-binding protein (CRALBP).1 RLBP1 is a 36kDa water soluble protein and is expressed exclusively in retina and pineal gland. |
| General description: | The protein encoded by this gene is a 36kDa water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. (provided by RefSeq) |
| Immunogen: | RLBP1 (NP_000317.1, 1 a.a. ~ 317 a.a) full-length human protein. Sequence MSEGVGTFRMVPEEEQELRAQLEQL |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |