Anti-SLC6A4 antibody produced in rabbit
SIGMA/SAB1411290 - purified immunoglobulin, buffered aqueous solution
Synonym: 5-HTT; 5HTT; HTT; OCD1; SERT; hSERT
Product Type: Chemical
Western Blotting Western Blot analysis of SLC6A4 expression in transfected 293T cell line by SLC6A4 polyclonal antibody. Lanes Lane 1: SLC6A4 transfected lysate (70.30 kDa). Lane 2: Non-transfected lysate.
Western Blotting SLC6A4 rabbit polyclonal antibody. Western Blot analysis of SLC6A4 expression in mouse lung.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 70.3 kDa |
| NCBI accession no. | NM_001045.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P31645 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. (provided by RefSeq) |
| Immunogen: | SLC6A4 (AAH69484.1, 1 a.a. ~ 630 a.a) full-length human protein. Sequence METTPLNSQKQLSACEDGEDCQENG |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |