Anti-TNFRSF1B antibody produced in rabbit
SIGMA/SAB1411354 - purified immunoglobulin, buffered aqueous solution
Synonym: CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75
Product Type: Chemical
Western Blotting Western Blot analysis of TNFRSF1B expression in transfected 293T cell line by TNFRSF1B polyclonal antibody. Lanes Lane 1: TNFRSF1B transfected lysate (48.30 kDa). Lane 2: Non-transfected lysate.
Western Blotting TNFRSF1B rabbit polyclonal antibody. Western Blot analysis of TNFRSF1B expression in mouse testis.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 48.3 kDa |
| NCBI accession no. | NM_001066   |
| shipped in | dry ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P20333 |
| General description: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. (provided by RefSeq) |
| Immunogen: | TNFRSF1B (NP_001057.1, 1 a.a. ~ 461 a.a) full-length human protein. Sequence MAPVAVWAALAVGLELWAAAHALPA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |