Anti-TNNT1 antibody produced in rabbit
SIGMA/SAB1411357 - purified immunoglobulin, buffered aqueous solution
Synonym: ANM; FLJ98147; MGC104241; STNT; TNT; TNTS
Product Type: Chemical
Western Blotting TNNT1 rabbit polyclonal antibody. Western Blot analysis of TNNT1 expression in human placenta.
Western Blotting TNNT1 rabbit polyclonal antibody. Western Blot analysis of TNNT1 expression in mouse kidney.
Western Blotting Western Blot analysis of TNNT1 expression in transfected 293T cell line by TNNT1 polyclonal antibody. Lanes Lane 1: TNNT1 transfected lysate (31.20 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 31.2 kDa |
| NCBI accession no. | BC010963   |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P13805 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) |
| Immunogen: | TNNT1 (AAH10963.1, 1 a.a. ~ 262 a.a) full-length human protein. Sequence MSDTEEQEYEEEQPEEEAAEEEEEA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |