Anti-TYR antibody produced in rabbit
SIGMA/SAB1411374 - purified immunoglobulin, buffered aqueous solution
Synonym: OCA1A; OCAIA; SHEP3
Product Type: Chemical
Western Blotting TYR rabbit polyclonal antibody. Western Blot analysis of TYR expression in HepG2.
Western Blotting Western Blot analysis of TYR expression in transfected 293T cell line by TYR polyclonal antibody. Lanes Lane 1: TYR transfected lysate (42.90 kDa). Lane 2: Non-transfected lysate.
Western Blotting TYR rabbit polyclonal antibody. Western Blot analysis of TYR expression in mouse kidney.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 42.9 kDa |
| NCBI accession no. | BC027179.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P14679 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3′ half of this gene. (provided by RefSeq) |
| Immunogen: | TYR (AAH27179.1, 1 a.a. ~ 377 a.a) full-length human protein. Sequence MLLAVLYCLLWSFQTSAGHFPRACV |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |