Anti-RFXANK antibody produced in rabbit
SIGMA/SAB1411547 - purified immunoglobulin, buffered aqueous solution
Synonym: ANKRA1; BLS; F14150_1; MGC138628; RFX-B
Product Type: Chemical
Western Blotting Western Blot analysis of RFXANK expression in transfected 293T cell line by RFXANK polyclonal antibody. Lanes Lane 1: RFXANK transfected lysate (25.60 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 25.6 kDa |
| NCBI accession no. | NM_134440.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | O14593 |
| General description: | Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. (provided by RefSeq) |
| Immunogen: | RFXANK (NP_604389.1, 1 a.a. ~ 237 a.a) full-length human protein. Sequence MELTQPAEDLIQTQQTPASELGDPE |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |