Anti-ADAMTS4 antibody produced in rabbit
SIGMA/SAB1411668 - purified immunoglobulin, buffered aqueous solution
Synonym: ADAMTS-2; ADAMTS-4; ADMP-1; KIAA0688
Product Type: Chemical
Western Blotting Western Blot analysis of ADAMTS4 expression in transfected 293T cell line by ADAMTS4 polyclonal antibody. Lanes Lane 1: ADAMTS4 transfected lysate (36.00 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 36 kDa |
| NCBI accession no. | BC030812.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | O75173 |
| General description: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. (provided by RefSeq) |
| Immunogen: | ADAMTS4 (AAH30812.1, 1 a.a. ~ 339 a.a) full-length human protein. Sequence MSQTGSHPGRGLAGRWLWGAQPCLL |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |