ANTI-ZSCAN21 antibody produced in mouse
SIGMA/SAB1412085 - clone 4B11, purified immunoglobulin, buffered aqueous solution
Synonym: DKFZp434L134; DKFZp686H10254; NY-REN-21; ZNF38; ZSCAN21
Product Type: Chemical
Western Blotting Western Blot analysis of ZSCAN21 expression in transfected 293T cell line by ZNF38 monoclonal antibody, clone 4B11. Lanes Lane 1: ZSCAN21 transfected lysate (Predicted MW: 53.7 kDa). Lane 2: Non-transfected lysate.
ELISA Detection limit for recombinant GST tagged ZSCAN21 is 0.1 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4B11, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen 77.55 kDa |
| NCBI accession no. | BC047309   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9Y5A6 |
| Biochem/physiol Actions: | The gene ZSCAN21 (zinc finger and SCAN domain containing 21) encodes a transcription factor that transcriptionally regulates the gene SNCA that encodes α-synuclein in primary neuronal cultures. α-Synuclein is a presynaptic neuronal protein that is associated with Parkinson disease (PD). Therefore, the ZSCAN21 gene may serve as a potential target in the treatment of PD. |
| General description: | The gene ZSCAN21 (zinc finger and SCAN domain containing 21), also referred to as NY-REN-21, encodes a C2H2 type multi-finger protein that contains an N-terminal SCAN (SRE-ZBP, CTfin51, AW-1 (ZNF174), and Number 18 cDNA or ZnF20) domain and a predicted coil at the central region. The SCAN domain has the ability to form homodimers. |
| Immunogen: | ZSCAN21 (AAH47309.1, 1 a.a. ~ 473 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MMTKVLGMAPVLGPRPPQEQVGPLM |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |