ANTI-TLR9 antibody produced in mouse
SIGMA/SAB1412156 - clone 2H5, purified immunoglobulin, buffered aqueous solution
Synonym: CD289; TLR9
Product Type: Chemical
Western Blotting TLR9 monoclonal antibody, clone 2H5 Western Blot analysis of TLR9 expression in NIH/3T3.
Western Blotting TLR9 monoclonal antibody, clone 2H5 Western Blot analysis of TLR9 expression in IMR-32.
ELISA Detection limit for recombinant GST tagged TLR9 is approximately 3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2H5, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen 38.5 kDa |
| NCBI accession no. | BC032713   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9NR96 |
| General description: | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. (provided by RefSeq) |
| Immunogen: | TLR9 (AAH32713, 99 a.a. ~ 215 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence PPVGLSPMHFPCHMTIEPSTFLAVP |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |