ANTI-TBX18 antibody produced in mouse
SIGMA/SAB1412362 - clone 4D3, purified immunoglobulin, buffered aqueous solution
Synonym: TBX18
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to TBX18 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting TBX18 monoclonal antibody, clone 4D3. Western Blot analysis of TBX18 expression in PC-12.
Western Blotting TBX18 monoclonal antibody, clone 4D3. Western Blot analysis of TBX18 expression in NIH/3T3.
Western Blotting TBX18 monoclonal antibody, clone 4D3 Western Blot analysis of TBX18 expression in HeLa S3 NE.
Western Blotting QC Western Blot detection against Immunogen (37.77 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4D3, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen 37.4 kDa |
| NCBI accession no. | XM_496819   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | , human, |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O95935 |
| Application: | ANTI-TBX18 antibody produced in mouse has been used in immunofluorescence staining. |
| Biochem/physiol Actions: | T-box transcription factor 18 (TBX18) is involved in the sinoatrial node (SAN) formation and is expressed in the development and differentiation stages. It is a crucial factor for the pacemaker cell formation from cardiomyocytes. TBX18 may be implicated in congenital heart defects and congenital anomalies of the kidneys and urinary tract (CAKUT). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | T-box transcription factor 18 (TBX18) belongs to the TBX family of transcription factors. It contains a conserved T-box domain and an N-terminal nuclear localization signal (NLS). The TBX18 gene is mapped to human chromosome 6q14.3 |
| Immunogen: | TBX18 (XP_496819, 454 a.a. ~ 560 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence STLLQGTGNGVPATHPHLLSGSSCS |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |