ANTI-ZIC2 antibody produced in mouse
SIGMA/SAB1412627 - clone 4A7, purified immunoglobulin, buffered aqueous solution
Synonym: HPE5; ZIC2
Product Type: Chemical
Immunoblotting Monoclonal Anti-ZIC2: Cat. No. SAB1412627: Antibody concentration: 1 μg/mL. Specific band of ~33.3 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (33.26 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4A7, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen 32.89 kDa |
| NCBI accession no. | NM_007129   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O95409 |
| General description: | This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. (provided by RefSeq) |
| Immunogen: | ZIC2 (NP_009060, 151 a.a. ~ 216 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence SDAQGHLLFP GLPEQHGPHG SQNVLNGQMR LGLPGEVFGR SEQYRQ VASP RTDPY |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |