Anti-SAG antibody produced in mouse
SIGMA/SAB1412744 - purified immunoglobulin
Synonym: Anti-DKFZp686D1084; Anti-DKFZp686I1383; Anti-S-AG
Product Type: Product-on-demand
Western Blotting Western Blot analysis of SAG expression in transfected 293T cell line by SAG polyclonal antibody. Lanes Lane 1: SAG transfected lysate (44.55 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | BC156656.1   |
| mol wt | antigen 44.55 kDa |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P10523 |
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| General description: | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. (provided by RefSeq) |
| Immunogen: | SAG (AAI56657.1, 1 a.a. ~ 405 a.a) full-length human protein. Sequence MAASGKTSKSEPNHVIFKKISRDKS |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |