Anti-HYAL2 antibody produced in mouse
SIGMA/SAB1412768 - purified immunoglobulin
Synonym: Anti-LUCA2; Anti-LuCa-2
Product Type: Product-on-demand
Western Blotting Western Blot analysis of HYAL2 expression in transfected 293T cell line by HYAL2 polyclonal antibody. Lanes Lane 1: HYAL2 transfected lysate (52.03 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | DQ893838.2   |
| mol wt | antigen 52.03 kDa |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q12891 |
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| General description: | This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. Varying functions have been described for this protein. It has been described as a lysosomal hyaluronidase which is active at a pH below 4 and specifically hydrolyzes high molecular weight hyaluronan. It has also been described as a GPI-anchored cell surface protein which does not display hyaluronidase activity but does serve as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5′ UTR. (provided by RefSeq) |
| Immunogen: | HYAL2 (ABM84764.1, 1 a.a. ~ 473 a.a) full-length human protein. Sequence MRAGPGPTVTLALVLAVAWAMELKP |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |