Anti-AKR1B1 antibody produced in rabbit
SIGMA/SAB2100091 - affinity isolated antibody
Synonym: Anti-ADR; Anti-ALDR1; Anti-ALR2; Anti-AR; Anti-Aldo-keto reductase family 1, member B1 (aldose reductase)
MDL Number: MFCD01321686
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of AKR1B1 in Human heart with AKR1B1 antibody at 4-8 μg/mL
Immunoblotting Anti-AKR1B1: Cat. No.SAB2100091: AKR1B1 in MCF7 cell lysate with AKR1B1 antibody at 1.0 μg/mL.
Western Blotting Western Blot of AKR1B1 in Mouse Skeletal Muscle with AKR1B1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 36 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | rat, human, mouse, horse, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P15121  |
| Biochem/physiol Actions: | AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human AKR1B1 |
| Other Notes: | Synthetic peptide located within the following region: ASRLLLNNGAKMPILGLGTWKSPPG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |