Anti-ALKBH3 antibody produced in rabbit
SIGMA/SAB2100108 - affinity isolated antibody
Synonym: Anti-ABH3; Anti-AlkB, alkylation repair homolog 3 (E. coli); Anti-DEPC1; Anti-MGC118790
Product Type: Chemical
Immunoblotting Anti-ALKBH3: Cat. No.SAB2100108: ALKBH3 in Fetal Muscle tissue lysate with ALKBH3 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 33 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human, pig, rat, mouse, horse |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q96Q83  |
| Biochem/physiol Actions: | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5′ end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1519 AB042029.1 2-1520 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human ALKBH3 |
| Other Notes: | Synthetic peptide located within the following region: EMRKKPPPEENGDYTYVERVKIPLD |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |