Anti-BHLHB3 antibody produced in rabbit
SIGMA/SAB2100217 - affinity isolated antibody
Synonym: Anti-Basic helix-loop-helix domain containing, class B, 3; Anti-SHARP1
MDL Number: MFCD03097265
Product Type: Chemical
Immunoblotting Anti-BHLHB3: Cat. No.SAB2100217: BHLHB3 in HepG2 cell lysate with BHLHB3 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 50 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human, pig, dog |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9C0J9  |
| Biochem/physiol Actions: | BHLHB3 may be a transcriptional repressor that represses both basal and activated transcription. It play a role as a tumor suppressor for lung cancer. DEC1 and DEC2(BHLHB3) may play a crucial role in the adaptation to hypoxia and are regulators of the mammalian molecular clock, and form a fifth clock-gene family. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human BHLHB3 |
| Other Notes: | Synthetic peptide located within the following region: YCVPVIQRTQPSAELAAENDTDTDS |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |