Anti-CPEB4 antibody produced in rabbit
SIGMA/SAB2100474 - affinity isolated antibody
Synonym: Anti-Cytoplasmic polyadenylation element binding protein 4; Anti-KIAA1673
Product Type: Chemical
Immunoblotting Anti-CPEB4: Cat. No.SAB2100474: CPEB4 in Fetal Lung tissue lysate with CPEB4 antibody at 1.0 μg/mL.
Immunoblotting CPEB4 Antibody: Cat. No. SAB2100474: Western Blot analysis of CPEB4 in Human Lung cell lysates with CPEB4 Antibody at 1.0 μg/mL.
Western Blotting Western Blot of CPEB4 in Human Daudi with CPEB4 antibody at 1 μg/mL
Western Blotting Western Blot of CPEB4 in Human Raji with CPEB4 antibody at 1 μg/mL
Western Blotting Western Blot of CPEB4 in Human DLD1 Whole Cell with CPEB4 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 80 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human, dog, mouse, guinea pig, rabbit, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q17RY0  |
| Biochem/physiol Actions: | Cytoplasmic polyadenylation element-binding protein 4 (CPEB4) plays a key role in translational control during tumor development and modulates various biological processes in tumor progression, including invasion, metastasis, tumor cell growth, and vascularization. It is involved in pathologic angiogenesis, terminal erythroid differentiation, and non-neuronal tissues for cancer progression. Overexpression of the CPEB4 gene is associated with pancreatic ductal adenocarcinoma and glioblastoma. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Cytoplasmic polyadenylation element-binding protein 4 (CPEB4) is a sequence-specific binding protein that belongs to the CPEB family. It consists of two domains, an unstructured domain, and a RNA binding domain. CPEB4 is expressed in the spinal cord and brain. The CPEB4 gene is mapped on the human chromosome at 5q35.2. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human CPEB4 |
| Other Notes: | Synthetic peptide located within the following region: DEILGSEKAKSQQQEQQDPLEKQQL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |