Anti-CTH antibody produced in rabbit
SIGMA/SAB2100501 - affinity isolated antibody
Synonym: Anti-Cystathionase (cystathionine γ-lyase); Anti-MGC9471
Product Type: Chemical
Immunoblotting Anti-CTH: Cat. No.SAB2100501: CTH in Transfected 293T cell lysate with CTH antibody at 1.0 μg/mL.
Western Blotting Western Blot of CTH in Human K562 cell lysate with CTH antibody at 1 μg/mL
Western Blotting Western Blot of CTH in Human HCT116 Whole Cell with CTH antibody at 1 μg/mL
Western Blotting Western Blot of CTH in Human 786-0 Whole Cell with CTH antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 44 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | bovine, mouse, dog, human, rabbit, rat, pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P32929  |
| Biochem/physiol Actions: | CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human CTH |
| Other Notes: | Synthetic peptide located within the following region: VPPISLSTTFKQGAPGQHSGFEYSR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |