Anti-DEGS1 antibody produced in rabbit
SIGMA/SAB2100559 - affinity isolated antibody
Synonym: Anti-DEGS; Anti-DES1; Anti-Degenerative spermatocyte homolog 1, lipid desaturase (Drosophila); Anti-FADS7
Product Type: Chemical
Immunohistochemistry DEGS1 Antibody: Cat. No. SAB2100559: Immunohistochemistry analysis of DEGS1 in Human Lung Tissue with DEGS1 Antibody 1.0 μg/mL. Observed Staining: Cytoplasm of pneumocytes
Immunoblotting Anti-DEGS1: Cat. No.SAB2100559: DEGS1 in Fetal Muscle tissue lysate with DEGS1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 38 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | guinea pig, mouse, horse, bovine, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | O15121  |
| Biochem/physiol Actions: | DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human DEGS1 |
| Other Notes: | Synthetic peptide located within the following region: GSRVSREDFEWVYTDQPHADRRREI |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |