Anti-DGCR8 antibody produced in rabbit
SIGMA/SAB2100567 - affinity isolated antibody
Synonym: Anti-C22orf12; Anti-DGCRK6; Anti-DiGeorge syndrome critical region gene 8; Anti-Gy1
Product Type: Chemical
Immunohistochemistry Anti-DGCR8: Cat. No. SAB2100567: Immunohistochemistry of DGCR8 in Liver tissue with DGCR8 antibody at 4-8 μg/mL.
Immunoblotting Anti-DGCR8: Cat. No.SAB2100567: DGCR8 in HeLa cell lysate with DGCR8 antibody at 1.0 μg/mL.
Immunoblotting DGCR8 Antibody: Cat. No. SAB2100567: Western Blot analysis of DGCR8 in Human Liver cell lysates with DGCR8 Antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 85 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse, guinea pig, rat, dog, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q8WYQ5  |
| Application: | Anti-DGCR8 antibody produced in rabbit is suitable for western blot analysis. |
| Biochem/physiol Actions: | DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human DGCR8 |
| Other Notes: | Synthetic peptide located within the following region: DKKDEENELDQEKRVEYAVLDELED |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |