Anti-EPOR antibody produced in rabbit
SIGMA/SAB2100693 - affinity isolated antibody
Synonym: Anti-Erythropoietin receptor; Anti-MGC138358
MDL Number: MFCD01092334
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of EPOR in Human Bone Marrow with EPOR antibody at 4-8 μg/mL
Immunoblotting Anti-EPOR: Cat. No.SAB2100693: EPOR in Fetal Brain tissue lysate with EPOR antibody at 1.0 μg/mL.
Western Blotting Western Blot of EPOR in Mouse Small Intestine with EPOR antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| InChI | 1S/C40H74O3/c1-3-5-7-9-11 |
| InChI key | QLXNJYBNAORLFC-CLFAGFIQSA |
| mol wt | 53 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| SMILES string | O(C(=O)CCCCCCCCCC=C/CCCC |
| species reactivity | human, mouse, dog, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P19235  |
| Application: | Anti-EPOR antibody produced in rabbit has been used in immunoblot analysis and magnetic cell sorting. |
| Biochem/physiol Actions: | The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human EPOR |
| Other Notes: | Synthetic peptide located within the following region: DHLGASLWPQVGSLCLLLAGAAWAP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |