Anti-ESR2 antibody produced in rabbit
SIGMA/SAB2100713 - affinity isolated antibody
Synonym: Anti-ER-β; Anti-ESR-β; Anti-ESRB; Anti-ESTRB; Anti-Estrogen receptor 2 (ER β)
MDL Number: MFCD01323253
Product Type: Chemical
Immunoblotting Anti-ESR2: Cat. No.SAB2100713: ESR2 in HeLa cell lysate with ESR2 antibody at 1.0 μg/mL.
Immunoblotting ESR2: Cat. No. SAB2100713: Western blot analysis of ESR2 in Human Adult Placenta cell lysates with ESR2 antibody at 1.0 μg/mL.
Immunoblotting ESR2: Cat. No. SAB2100713: Western blot analysis of ESR2 in Human 293T cell lysates with ESR2 antibody at 1.0 μg/mL.
Immunoblotting ESR2: Cat. No. SAB2100713: Western blot analysis of ESR2 in Human Fetal Muscle cell lysates with ESR2 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 59 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q92731  |
| Biochem/physiol Actions: | ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. It contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human ESR2 |
| Other Notes: | Synthetic peptide located within the following region: EYLCVKAMILLNSSMYPLVTATQDA |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |