Anti-GJC2 antibody produced in rabbit
SIGMA/SAB2100924 - affinity isolated antibody
Synonym: Anti-CX46.6; Anti-Cx47; Anti-GJA12; Anti-Gap junction protein, γ 2, 47kDa; Anti-MGC105119
Product Type: Chemical
Immunohistochemistry GJC2 Antibody: Cat. No. SAB2100924: Immunohistochemistry analysis of GJC2 in heart with GJC2 Antibody 5.0 μg/mL. Observed Staining: Membrane, some cytoplasm
Immunoblotting Anti-GJC2: Cat. No.SAB2100924: GJC2 in MCF7 cell lysate with GJC2 antibody at 1.0 μg/mL.
Immunoblotting GJC2 Antibody: Cat. No. SAB2100924: Western Blot analysis of GJC2 in Human MCF-7 cell lysates with GJC2 Antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 47 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q5T442  |
| Biochem/physiol Actions: | GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human GJC2 |
| Other Notes: | Synthetic peptide located within the following region: APASRTGSATSAGTVGEQGRPGTHE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |