Anti-HNF4A antibody produced in rabbit
SIGMA/SAB2101055 - affinity isolated antibody
Synonym: Anti-FLJ39654; Anti-HNF4; Anti-HNF4a7; Anti-HNF4a8; Anti-Hepatocyte nuclear factor 4, α
Product Type: Chemical
Immunoblotting Anti-HNF4A: Cat. No.SAB2101055: HNF4A in HeLa cell lysate with HNF4A antibody at 1.0 μg/mL.
Immunoblotting HNF4A: Cat. No. SAB2101055: Western blot analysis of HNF4A in Human Adult Placenta cell lysates with HNF4A antibody at 1.0 μg/mL.
Western Blotting Western Blot of HNF4A in Human Adult Placenta with HNF4A antibody at 1 μg/mL
Western Blotting Western Blot of HNF4A in Rat Skeletal Muscle with HNF4A antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 49 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | horse, mouse, sheep, rat, dog, guinea pig, human, rabbit, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P41235  |
| Biochem/physiol Actions: | The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human HNF4A |
| Other Notes: | Synthetic peptide located within the following region: LPFQELQIDDNEYAYLKAIIFFDPD |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |