Anti-IMPDH1 antibody produced in rabbit
SIGMA/SAB2101156 - affinity isolated antibody
Synonym: Anti-DKFZp781N0678; Anti-IMP (inosine monophosphate) dehydrogenase 1; Anti-IMPD; Anti-LCA11
Product Type: Chemical
Immunohistochemistry Anti-IMPDH1: Cat. No. SAB2101156: Immunohistochemistry of IMPDH1 in Human Colon tissue with IMPDH1 antibody at 5.0 μg/mL.
Immunoblotting Anti-IMPDH1: Cat. No.SAB2101156: IMPDH1 in HeLa cell lysate with IMPDH1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 62 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | bovine, dog, mouse, rabbit, rat, guinea pig, horse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified, unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P20839  |
| Biochem/physiol Actions: | IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5′-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human IMPDH1 |
| Other Notes: | Synthetic peptide located within the following region: KKGKLPIVNDCDELVAIIARTDLKK |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |