Anti-JAG2 antibody produced in rabbit
SIGMA/SAB2101188 - affinity isolated antibody
Synonym: Anti-HJ2; Anti-Jagged 2
Product Type: Chemical
Immunohistochemistry JAG2 Antibody: Cat. No. SAB2101188: Immunohistochemistry analysis of JAG2 in Human Bronchial Epithelial Tissue with JAG2 Antibody 5.0 μg/mL. Observed Staining: Membrane of bronchial epithelial tissue
Immunoblotting Anti-JAG2: Cat. No.SAB2101188: JAG2 in Jurkat cell lysate with JAG2 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 130 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse, human, rat, pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9Y219  |
| Biochem/physiol Actions: | The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch protein family are transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human JAG2 |
| Other Notes: | Synthetic peptide located within the following region: RAQGRGRLPRRLLLLLALWVQAARP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |