Anti-LCP1 (ab2) antibody produced in rabbit
SIGMA/SAB2101328 - affinity isolated antibody
Synonym: Anti-CP64; Anti-DKFZp781A23186; Anti-FLJ25423; Anti-FLJ26114; Anti-Lymphocyte cytosolic protein 1 (L-plastin)
Product Type: Chemical
Immunoblotting Anti-LCP1 (ab2): Cat. No.SAB2101328: LCP1 in Placenta tissue lysate with LCP1 antibody at 1.0 μg/mL.
Western Blotting Western Blot of LCP1 in Human Jurkat with LCP1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 70 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human, rabbit, bovine, dog, rat, mouse, horse, pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified, unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P13796  |
| Biochem/physiol Actions: | Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human LCP1 |
| Other Notes: | Synthetic peptide located within the following region: ILEEIGGGQKVNDDIIVNWVNETLR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |