Anti-NR0B1 antibody produced in rabbit
SIGMA/SAB2101627 - affinity isolated antibody
Synonym: Anti-AHC; Anti-AHCH; Anti-AHX; Anti-DAX-1; Anti-Nuclear receptor subfamily 0, group B, member 1
Product Type: Chemical
Immunohistochemistry Anti-NR0B1: Cat. No. SAB2101627: Immunohistochemistry of NR0B1 in Human Testis tissue with NR0B1 antibody at 5.0 μg/mL.
Immunoblotting Anti-NR0B1: Cat. No.SAB2101627: NR0B1 in MCF7 cell lysate with NR0B1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 52 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | bovine, mouse, guinea pig, human, dog, horse, rabbit, rat |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9BG96  |
| Biochem/physiol Actions: | NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human NR0B1 |
| Other Notes: | Synthetic peptide located within the following region: QAIKCFLSKCWSLNISTKEYAYLKG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |