Anti-NR4A1 antibody produced in rabbit
SIGMA/SAB2101650 - affinity isolated antibody
Synonym: Anti-GFRP1; Anti-HMR; Anti-MGC9485; Anti-N10; Anti-Nuclear receptor subfamily 4, group A, member 1
MDL Number: MFCD01865040
Product Type: Chemical
Immunohistochemistry Anti-NR4A1: Cat. No. SAB2101650: Immunohistochemistry of NR4A1 in Adrenal tissue with NR4A1 antibody at 4-8 μg/mL.
Immunoblotting Anti-NR4A1: Cat. No.SAB2101650: NR4A1 in HepG2 cell lysate with NR4A1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 64 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | dog, guinea pig, rabbit, rat, human, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P22736  |
| Biochem/physiol Actions: | NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human NR4A1 |
| Other Notes: | Synthetic peptide located within the following region: FQKCLAVGMVKEVVRTDSLKGRRGR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |