Anti-RAPGEF1 antibody produced in rabbit
SIGMA/SAB2101945 - affinity isolated antibody
Synonym: Anti-C3G; Anti-DKFZp781P1719; Anti-GRF2; Anti-Rap guanine nucleotide exchange factor (GEF) 1
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of RAPGEF1 in Human Placenta with RAPGEF1 antibody at 4-8 μg/mL
Immunohistochemistry Immunohistochemistry of RAPGEF1 in Human Tonsil with RAPGEF1 antibody at 4-8 μg/mL
Immunoblotting Anti-RAPGEF1: Cat. No.SAB2101945: RAPGEF1 in Fetal Brain tissue lysate with RAPGEF1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 120 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | dog, horse, rat, bovine, mouse, guinea pig, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q13905  |
| Biochem/physiol Actions: | RAPGEF1 is a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade protein may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human RAPGEF1 |
| Other Notes: | Synthetic peptide located within the following region: LWAKEQNEEKSPNLTQFTEHFNNMS |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |