Anti-RORA (ab1) antibody produced in rabbit
SIGMA/SAB2102038 - affinity isolated antibody
Synonym: Anti-MGC119326; Anti-MGC119329; Anti-NR1F1; Anti-RAR-related orphan receptor A; Anti-ROR1
Product Type: Chemical
Immunoblotting Anti-RORA (ab1): Cat. No.SAB2102038: RORA in 721_B cell lysate with RORA antibody at 1.0 μg/mL.
Immunoblotting RORA: Cat. No. SAB2102038: Western blot analysis of RORA in Human Fetal Heart cell lysates with RORA antibody at 1.0 μg/mL.
Immunoblotting RORA: Cat. No. SAB2102038: Western blot analysis of RORA in Human Adult Placenta cell lysates with RORA antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 53 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse, horse, human, goat, guinea pig, dog, rat, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P35398  |
| Biochem/physiol Actions: | The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human RORA |
| Other Notes: | Synthetic peptide located within the following region: GFMELCQNDQIVLLKAGSLEVVFIR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |