Anti-RUNX1 (ab2) antibody produced in rabbit
SIGMA/SAB2102064 - affinity isolated antibody
Synonym: Anti-AML1; Anti-AML1-EVI-1; Anti-AMLCR1; Anti-CBFA2; Anti-Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)
MDL Number: MFCD07370485
Product Type: Chemical
Immunoblotting Anti-RUNX1 (ab2): Cat. No.SAB2102064: RUNX1 in Jurkat cell lysate with RUNX1 antibody at 1.0 μg/mL.
Immunoblotting RUNX1: Cat. No. SAB2102064: Western blot analysis of RUNX1 in Human Fetal Muscle cell lysates with RUNX1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 52 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | dog, rabbit, guinea pig, rat, bovine, human, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q01196  |
| Application: | Anti-RUNX1 (ab2) antibody produced in rabbit is suitable for western blot. |
| Biochem/physiol Actions: | Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia. Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The previously assigned protein identifier B2RMS4 has been merged into Q01196. Full details can be found on the UniProt database. |
| Immunogen: | Synthetic peptide directed towards the middle region of human RUNX1 |
| Other Notes: | Synthetic peptide located within the following region: CTNASTGSALLNPSLPNQSDVVEAE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |