Anti-SDHB antibody produced in rabbit
SIGMA/SAB2102103 - affinity isolated antibody
Synonym: Anti-IP; Anti-PGL4; Anti-SDH; Anti-SDH1; Anti-Succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
MDL Number: MFCD02263389
Product Type: Chemical
Immunoblotting Anti-SDHB: Cat. No.SAB2102103: SDHB in Jurkat cell lysate with SDHB antibody at 1.0 μg/mL.
Immunoblotting SDHB: Cat. No. SAB2102103: Western blot analysis of SDHB in Human Adult Placenta cell lysates with SDHB antibody at 1.0 μg/mL.
Immunoblotting SDHB: Cat. No. SAB2102103: Western blot analysis of SDHB in Human Fetal Heart cell lysates with SDHB antibody at 1.0 μg/mL.
Immunoblotting SDHB: Cat. No. SAB2102103: Western blot analysis of SDHB in Human Fetal Liver cell lysates with SDHB antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 31 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | horse, rat, dog, goat, mouse, bovine, rabbit, human, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P21912  |
| Biochem/physiol Actions: | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human SDHB |
| Other Notes: | Synthetic peptide located within the following region: YRWMIDSRDDFTEERLAKLQDPFSL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |