Anti-SFTPB antibody produced in rabbit
SIGMA/SAB2102128 - affinity isolated antibody
Synonym: Anti-PSP-B; Anti-SFTB3; Anti-SFTP3; Anti-SMDP1; Anti-Surfactant, pulmonary-associated protein B
Product Type: Chemical
Immunohistochemistry SFTPB Antibody: Cat. No. SAB2102128: Immunohistochemistry analysis of SFTPB in Human Lung Tissue with SFTPB Antibody 1.0 μg/mL. Observed Staining: Cytoplasm and membrane of pneumocytes
Immunoblotting Anti-SFTPB: Cat. No.SAB2102128: SFTPB in 721_B cell lysate with SFTPB antibody at 1.0 μg/mL.
Western Blotting Western Blot of SFTPB in Mouse Liver with SFTPB antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 42 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | dog, guinea pig, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | B2RC55  |
| Biochem/physiol Actions: | SFTPB is the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins. See also SFTPA1, SFTPC, and SFTPD. The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human SFTPB |
| Other Notes: | Synthetic peptide located within the following region: PGALQARPGPHTQDLSEQQFPIPLP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |