Anti-TFR2 (ab2) antibody produced in rabbit
SIGMA/SAB2102415 - affinity isolated antibody
Synonym: Anti-HFE3; Anti-MGC126368; Anti-TFRC2; Anti-Transferrin receptor 2
Product Type: Chemical
Immunohistochemistry Anti-TFR2 (ab2): Cat. No. SAB2102415: Immunohistochemistry of TFR2 in Human Skin tissue with TFR2 antibody at 10 μg/mL.
Immunoblotting Anti-TFR2 (ab2): Cat. No.SAB2102415: TFR2 in Fetal Muscle tissue lysate with TFR2 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| form | buffered aqueous solution |
| mol wt | 89 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | bovine, guinea pig, rabbit, horse, mouse, dog, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9UP52  |
| Biochem/physiol Actions: | TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human TFR2 |
| Other Notes: | Synthetic peptide located within the following region: RAALSRQKLDHVWTDTHYVGLQFPD |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |