Anti-TRIB2 antibody produced in rabbit
SIGMA/SAB2102535 - affinity isolated antibody
Synonym: Anti-GS3955; Anti-TRB2; Anti-Tribbles homolog 2 (Drosophila)
Product Type: Chemical
Immunoblotting Anti-TRIB2: Cat. No.SAB2102535: TRIB2 in Fetal Liver tissue lysate with TRIB2 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 39 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | rat, rabbit, guinea pig, horse, mouse, human, bovine, dog |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q92519  |
| Biochem/physiol Actions: | TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human TRIB2 |
| Other Notes: | Synthetic peptide located within the following region: YPFHDIEPSSLFSKIRRGQFNIPET |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |